Last update
5/11/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin A (from fish [liver] oil, retinyl palmitate)
3,000 mcg
333%
Top Medical Research Studies
8
We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.
Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.
However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.
Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.
However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.
Read More
7
Vitamin A promotes vascular repair via JWA protein activation
Researchers investigated whether a form of vitamin A called atRA could help treat obstructive sleep apnea by studying rat models and cell cultures exposed to interrupted oxygen. They found that atRA boosts production of a protein called JWA, which reduces harmful oxidative stress damaging blood vessel linings in the lungs.
This oxidative stress reduction appears to restore normal function and growth of damaged blood vessels—a key problem in sleep apnea patients who often develop dangerous high blood pressure in their lungs. While these promising lab results suggest atRA could become a new treatment option for sleep apnea, further research in human patients would be needed to confirm these findings and establish safe, effective doses.
This oxidative stress reduction appears to restore normal function and growth of damaged blood vessels—a key problem in sleep apnea patients who often develop dangerous high blood pressure in their lungs. While these promising lab results suggest atRA could become a new treatment option for sleep apnea, further research in human patients would be needed to confirm these findings and establish safe, effective doses.
Read More
Most Useful Reviews
9
Improved sleep quality
I experience better sleep! The quality of my sleep is noticeably enhanced.
Read More
7.5
Sebum reduction
It has a positive effect on reducing sebum and aids in improving my sleep, so I take it in the evening.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.
Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.
However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.
Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.
However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.
Read More
7
Vitamin A promotes vascular repair via JWA protein activation
Researchers investigated whether a form of vitamin A called atRA could help treat obstructive sleep apnea by studying rat models and cell cultures exposed to interrupted oxygen. They found that atRA boosts production of a protein called JWA, which reduces harmful oxidative stress damaging blood vessel linings in the lungs.
This oxidative stress reduction appears to restore normal function and growth of damaged blood vessels—a key problem in sleep apnea patients who often develop dangerous high blood pressure in their lungs. While these promising lab results suggest atRA could become a new treatment option for sleep apnea, further research in human patients would be needed to confirm these findings and establish safe, effective doses.
This oxidative stress reduction appears to restore normal function and growth of damaged blood vessels—a key problem in sleep apnea patients who often develop dangerous high blood pressure in their lungs. While these promising lab results suggest atRA could become a new treatment option for sleep apnea, further research in human patients would be needed to confirm these findings and establish safe, effective doses.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved sleep quality
I experience better sleep! The quality of my sleep is noticeably enhanced.
Read More
7.5
Sebum reduction
It has a positive effect on reducing sebum and aids in improving my sleep, so I take it in the evening.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Saruhan E, Sertoglu E, Unal Y, Bek S, Kutlu G. The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea. Sleep Breath. 2021;25:923. 10.1007/s11325-020-02207-w
- Yan Y, Lan J, Zhang H, Ren Y, Cheng X, et al. JWA mediates oxidative stress to promote vascular endothelial repair in obstructive sleep apnea-hypopnea syndrome. Sleep Med. 2025;134:106686. 10.1016/j.sleep.2025.106686
